Eperythrozoon coccoides I. Effect on the Interferon Response in Mice
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چکیده
منابع مشابه
Eperythrozoon coccoides. I. Effect on the interferon response in mice.
Eperythrozoon coccoides is a common blood parasite of rodents and the etiological agent of a chronic infection present in many mouse colonies. After primary infection, mice develop a parasitemia and anemia followed by a chronic, latent infection. During the acute phase of infection, mice manifest a striking suppression of interferon production in response to induction with Newcastle disease vir...
متن کاملEperythrozoon coccoides. II. Effect on interferon production and role of humoral antibody in host resistance.
Eperythrozoon coccoides was shown to inhibit the interferon response in mice only during the first 3 weeks after acute infection. By 6 weeks the production of interferon in response to Newcastle disease virus returned to a normal level. Antibody to E. coccoides could be demonstrated by three methods: (i) neutralization, (ii) indirect fluorescent antibody, and (iii) gel diffusion. The clearance ...
متن کاملAgglutination of mouse erythrocytes by Eperythrozoon coccoides.
Erythrocytes from blood of mice infected with Eperythrozoon coccoides for 3 or 4 days agglutinated spontaneously. Washed E. coccoides particles agglutinated washed erythrocytes of uninfected mice. E. coccoides-mediated agglutination of normal mouse erythrocytes would be an excellent system for studies of bacterial adhesion.
متن کاملAn Ascites Tumor Appearing during the Passage of Eperythrozoon Coccoides in Mice
A strain of Eperythrozoon coccoides was maintained in a pure state for 16 months in unsplenectomized Princeton mice by the intraperitoneal injection of parasitized blood, at intervals of 1 to 3 weeks. In the 39th passage three out of five mice developed marked ascites with innumerable neoplastic cells in the peritoneal fluid. By passage of this fluid the tumor cells and the eperythrozoon were t...
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ژورنال
عنوان ژورنال: Infection and Immunity
سال: 1971
ISSN: 0019-9567,1098-5522
DOI: 10.1128/iai.4.4.425-430.1971